Dr. Jacques-Joseph Moreau (1804–1884) was a French psychiatrist and member of the Club des Hashischins. Moreau was the first physician to do systematic work on drugs' effects on the central nervous system, and to catalogue, analyze, and record his observations. His 1845 book, Hashish and Mental Alienation, is still applicable today. In 1843 with Jules Baillarger (1809–1890), François Achille Longet (1811–1871) and Laurent Alexis Philibert Cerise (1807–1869), he founded the psychiatric journal Annales médico-psychologiques.
"In an era which finally viewed the human psyche in a natural humanist terms rather than as the uncontrollable supernatural domain of demons and angels. Through careful observation of people's reactions, including his own, to hashish-particularly their openness to suggestions and willingness to consider new possibilities- Moreau theorized that psychoactive substances could treat or replicate mental illness in a way to help cure patients. His 1845 studies on dhatura and hashish were prepared as a treatise that documented both physical and mental benefits, and ultimately led to modern psychopharmacology and the use of numerous psychotomimetic drug treatments." ("Hemp for Health" Chris Conrad p 20)